FTP: Eli: I don't think it took rocket scientist either

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Week Seven was a very lucky week for yours truly.? With an unlucky 13 games on the schedule, I got 12 of them correct, with only a late comeback from the Titans blocking an unprecedented piece of perfection.

More importantly, MDS and I disagreed on three games.? Thanks to the Cowboys, Saints, and Colts, my two-game season-to-date lead has been extended to five games.

For the year, I?m now 67-37, and MDS is 62-42.

MDS will join Thursday?s PFT Live to discuss this week?s picks.? There will be no gloating.

At least not by him.

Buccaneers at Vikings

MDS?s take: After I was burned by picking the Bucs last week on the way to going 0-for-3 on games where I disagreed with Florio, I?m playing it safe this week. Tampa Bay still looks to me like a team that?s headed in the right direction, but right now the Vikings have too much for the Bucs on both sides of the ball and should win this one comfortably.

MDS?s pick: Vikings 27, Buccaneers 13.

Florio?s take:? The Vikings get a chance to show how different they are this year against one of the teams to whom the Vikings blew a big halftime lead last year.? This time, if the Vikings are up by 10 or more at the break, look for them to close it out with a defense that finally is good enough to hold leads.

Florio?s pick:? Vikings 21, Buccaneers 19.

Panthers at Bears

MDS?s take: Cam Newton is going to bounce back from this slump he?s in eventually. He?s too talented not to. But the Bears are the wrong team for a young quarterback to bounce back against. Chicago?s relentless pressure will force a few turnovers and lead to another loss for the Panthers.

MDS?s pick: Bears 20, Panthers 10.

Florio?s take:? Rattled by the ouster of G.M. Marty Hurney, racked by injuries, and reeling from the sad-sack demeanor of Cam Newton, the Panthers are poised to get plastered.

Florio?s pick:? Bears 31, Panthers 10.

Chargers at Browns

MDS?s take: The Chargers have had two weeks to lick their wounds after that disastrous Monday night meltdown against the Broncos. They?ll come in to Cleveland focused and motivated and win this one comfortably.

MDS?s pick: Chargers 31, Browns 17.

Florio?s take:? If Mike Holmgren?s current team can knock off the Chargers, the Chargers could be Mike Holmgren?s next team.? Though a house-cleaning could still be coming, the Chargers will likely do enough to reverse a bad two weeks of blown leads and stickum, allegedly.

Florio?s pick:? Chargers 24, Browns 17.

Seahawks at Lions

MDS?s take: Mistakes keep killing the Lions, whether it?s penalties, turnovers or special teams coverage breakdowns. If the Lions could get out of their own way they could go on a run down the stretch and still contend for a wild card berth, but that doesn?t look likely at this point. Seattle is the team that looks like a playoff contender, and the Seahawks will take another step in that direction with a win on the road.

MDS?s pick: Seahawks 17, Lions 14.

Florio?s take:? If this one were set for Seattle, it would be a no brainer.? In Detroit, the Seahawks have an opportunity to prove that they?re capable of beating better-than-bad teams in a place other than CenturyLink Field.

Florio?s pick:? Seahawks 17, Lions 16.

Jaguars at Packers

MDS?s take: In the biggest mismatch of the week, the Jaguars? offense will look even worse than usual without Maurice Jones-Drew, and Aaron Rodgers will have his third consecutive huge game.

MDS?s pick: Packers 34, Jaguars 3.

Florio?s take:? The Packers have never beaten the Jaguars at Lambeau Field.? Then again, these teams have played there only once.? The Jags will want to forget their second trip to town.

Florio?s pick:? Packers 45, Jaguars 21.

Dolphins at Jets

MDS?s take: I?m impressed that the Jets aren?t going down without a fight. When they lost Darrelle Revis and got blown out by the 49ers, I figured the Jets were finished, but they?ve played good football for the last three weeks, even if they have only one win to show for it in those three games. The Jets will beat the Dolphins in a low-scoring game and get back to .500.

MDS?s pick: Jets 13, Dolphins 10.

Florio?s take:? Despite the injuries and the ineffectiveness and the uncertainty, the Jets have improved over the past few weeks.? They?re good enough to complete the sweep of a Dolphins team that has improved even more discreetly.

Florio?s pick:? Jets 30, Dolphins 20.

Falcons at Eagles

MDS?s take: The Eagles know their backs are against the wall, and the Falcons have been scraping by with three straight close wins. This looks to me like the day when the Falcons? luck runs out, and the last unbeaten team in the league gets beaten.

MDS?s pick: Eagles 24, Falcons 21.

Florio?s take:? Andy Reid is 13-0 after the bye week.? Sometimes, there?s no need for elaboration.

Florio?s pick:? Eagles 24, Falcons 23.

Redskins at Steelers

MDS?s take: The Steelers took a big step toward the playoffs with last week?s win in Cincinnati, and I like them to keep it going against the Redskins. Look for Steelers tight end Heath Miller to have a big game against the Redskins? defense, just as Giants tight end Martellus Bennett, Vikings tight end Kyle Rudolph and Falcons tight end Tony Gonzalez have in the Redskins? last three games.

MDS?s pick: Steelers 28, Redskins 27.

Florio?s take:? The Steelers are 20-2-1 at Heinz Field against NFC teams.? But Heinz Field has never seen anything like RG3, who?ll run circles around a Polamalu-free Pittsburgh defense.

Florio?s pick:? Redskins 23, Steelers 20.

Patriots at Rams

MDS?s take: The Rams? secondary has been playing well and the Patriots? secondary has been leaving receivers wide open, and I?m tempted to pick the upset for that reason. But with Danny Amendola hurt I don?t think the Rams have the ammunition to take advantage of the Patriots? problems on defense, and I think New England?s running game can churn up yardage at Wembley Stadium and lead the Patriots to a low-scoring win.

MDS?s pick: Patriots 16, Rams 10.

Florio?s take:? The team whose name pays homage to the men who kicked the butts of the Brits like to kick butt in Britain.? Though it won?t be a blowout like it was three years ago against the Bucs, the Pats should be able to build a fourth-quarter lead.? And hold it.? For a change.

Florio?s pick:? Patriots 27, Rams 21.

Colts at Titans

MDS?s take: Titans running back Chris Johnson took advantage of a bad Bills defense last week, and he should be able to take advantage of a bad Colts defense this week. Johnson will go for about 150 yards and the Colts? offense won?t be able to keep up.

MDS?s pick: Titans 28, Colts 21.

Florio?s take:? The winner of this one won?t likely challenge the Texans for the division crown but would be very much alive for a wild-card berth.? The Titans continue their knack for playing in ? and winning ? exciting games.

Florio?s pick:? Titans 27, Colts 24.

Raiders at Chiefs

MDS?s take: I?m not a believer in Brady Quinn as the Chiefs? long-term answer at quarterback, but as a short-term fix who won?t turn the ball over as often as Matt Cassel, Quinn should be able to lead Kansas City to a home win over a bad team.

MDS?s pick: Chiefs 20, Raiders 16.

Florio?s take:? Oakland has won five straight times at Arrowhead Stadium.? With an extra week to prepare and everyone on the hot seat, if the Chiefs don?t beat the Raiders at home now, they possibly never will.

Florio?s pick:? Chiefs 24, Raiders 10.

Giants at Cowboys

MDS?s take: Completing a season sweep of the Giants would go a long way toward getting the Cowboys into playoff contention, but I don?t see it happening. The Cowboys? defense will miss linebacker Sean Lee, Giants quarterback Eli Manning will have a big day, and the Giants will improve to 4-0 all time at Cowboys Stadium.

MDS?s pick: Giants 31, Cowboys 20.

Florio?s take:? The Cowboys aren?t nearly as good as they were in Week One, when they beat the Giants in New Jersey.? The Giants are the same, but this time they won?t get complacent.

Florio?s pick:? Giants 35, Cowboys 27.

Saints at Broncos

MDS?s take: Two future Hall of Fame quarterbacks will be on the field in Denver, but Drew Brees has to play against a good Broncos secondary, while Peyton Manning gets to play against a terrible Saints secondary. Advantage Peyton.

MDS?s pick: Broncos 42, Saints 21.

Florio?s take:? When he was the head coach of the Panthers, John Fox held his own against Sean Payton?s Saints.? This time, Fox has a great quarterback ? and the Saints don?t have Payton.

Florio?s pick:? Broncos 38, Saints 28.

49ers at Cardinals

MDS?s take: The Cardinals? great start to the season may come to a screeching halt on Monday night.? A home loss to a division rival would be tough for Arizona to overcome, and a win at Arizona will be another step for the 49ers toward establishing themselves as the clear favorites to win the NFC West.

MDS?s pick: 49ers 20, Cardinals 13.

Florio?s take:? Once atop the NFC West, the Cardinals are close to completing their slide to the basement.? Blame it on the lack of a high-end quarterback and an offensive line to protect him.

Florio?s pick:? 49ers 24, Cardinals 13.

Source: http://profootballtalk.nbcsports.com/2012/10/24/eli-manning-i-dont-think-it-took-a-rocket-scientist-either/related/

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Results of the AIDA STEMI MRI sub-study presented at TCT 2012

Public release date: 25-Oct-2012
[ | E-mail | Share ]

Contact: Judy Romero
jromero@crf.org
Cardiovascular Research Foundation

Study confirms that intracoronary and intravenous use of abciximab during angioplasty yield similar results

MIAMI, FL OCTOBER 25, 2012 A study confirmed no differences in various measures of heart damage, according to cardiac magnetic resonance (MRI) imaging, in patients receiving the anti-clotting medication abxicimab directly into the heart (intracoronary) compared to those receiving it intravenously (IV). The results of the AIDA STEMI MRI sub-study were presented today the 24th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. Sponsored by the Cardiovascular Research Foundation, TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine.

The AIDA STEMI trial was a randomized, open-label, multicenter trial in 2,065 patients presenting with ST-elevation myocardial infarction (STEMI) comparing intracoronary (IC) versus intravenous (IV) abciximab during PCI with subsequent 12 hour intravenous infusion. Last year, researchers reported that the trial found that both methods yielded similar 90-day rates of all-cause mortality, recurrent heart attack or congestive heart failure.

Researchers enrolled 703 patients within the overall trial in a cardiac magnetic resonance imaging sub-study, one of the largest MRI sub-studies conducted in patients with STEMI. Cardiac MRI allows for a more sensitive investigation of the mechanistic and pathophysiological effects of STEMI therapies on myocardial damage and reperfusion injury.

Cardiac MRI was completed within four days after heart attack using a standardized protocol including edema imaging and late gadolinium enhancement. Researchers examined infarct size, myocardial salvage, microvascular obstruction and ventricular function to determine the potential benefits of intracoronary compared to intravenous application of abciximab.

The amount of myocardium at risk and final infarct size did not differ significantly between the IC versus the IV abciximab groups. Consequently, the myocardial salvage index was similar between the two groups. In further detailed analysis there were no differences in microvascular obstruction between both treatment groups.

"Results of this sub-study demonstrate that intracoronary as compared to intravenous abciximab did not result in a difference in myocardial damage or reperfusion injury," said lead investigator Holger Thiele, MD. Dr. Thiele is Co-Director of the University of Leipzig - Heart Center in Germany.

"These findings confirm similarities in the combined endpoint of death, reinfarction and congestive heart failure found between the two methods in the AIDA STEMI trial," Dr. Thiele said.

Dr. Thiele will present the AIDA STEMI MRI sub-study on Thursday October 25 at 12:30 PM EST in the Main Arena (Hall D) at the Miami Beach Convention Center.

###

The trial was funded by Lilly Germany, the University of Leipzig - Heart Center and Clinical Trial Centre, and the Federal Ministry of Education and Research. Dr. Thiele reported research funding from Terumo, Lilly, Maquet Cardiovascular, and Teleflex Medical; consulting for Maquet Cardiovascular and Avidal; and speaker honoraria for Lilly, AstraZeneca, Daiichi Sankyo, Boehringer Ingelheim, Maquet Cardiovascular, and The Medicines Company.

About CRF

The Cardiovascular Research Foundation (CRF) is an independent, academically focused nonprofit organization dedicated to improving the survival and quality of life for people with cardiovascular disease through research and education. Since its inception in 1991, CRF has played a major role in realizing dramatic improvements in the lives of countless numbers of patients by establishing the safe use of new technologies and therapies in interventional cardiovascular medicine.

Transcatheter Cardiovascular Therapeutics (TCT) is the annual scientific symposium of the Cardiovascular Research Foundation. TCT gathers leading medical researchers and clinicians from around the world to present and discuss the latest developments in the field.

For more information, visit www.crf.org.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 25-Oct-2012
[ | E-mail | Share ]

Contact: Judy Romero
jromero@crf.org
Cardiovascular Research Foundation

Study confirms that intracoronary and intravenous use of abciximab during angioplasty yield similar results

MIAMI, FL OCTOBER 25, 2012 A study confirmed no differences in various measures of heart damage, according to cardiac magnetic resonance (MRI) imaging, in patients receiving the anti-clotting medication abxicimab directly into the heart (intracoronary) compared to those receiving it intravenously (IV). The results of the AIDA STEMI MRI sub-study were presented today the 24th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. Sponsored by the Cardiovascular Research Foundation, TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine.

The AIDA STEMI trial was a randomized, open-label, multicenter trial in 2,065 patients presenting with ST-elevation myocardial infarction (STEMI) comparing intracoronary (IC) versus intravenous (IV) abciximab during PCI with subsequent 12 hour intravenous infusion. Last year, researchers reported that the trial found that both methods yielded similar 90-day rates of all-cause mortality, recurrent heart attack or congestive heart failure.

Researchers enrolled 703 patients within the overall trial in a cardiac magnetic resonance imaging sub-study, one of the largest MRI sub-studies conducted in patients with STEMI. Cardiac MRI allows for a more sensitive investigation of the mechanistic and pathophysiological effects of STEMI therapies on myocardial damage and reperfusion injury.

Cardiac MRI was completed within four days after heart attack using a standardized protocol including edema imaging and late gadolinium enhancement. Researchers examined infarct size, myocardial salvage, microvascular obstruction and ventricular function to determine the potential benefits of intracoronary compared to intravenous application of abciximab.

The amount of myocardium at risk and final infarct size did not differ significantly between the IC versus the IV abciximab groups. Consequently, the myocardial salvage index was similar between the two groups. In further detailed analysis there were no differences in microvascular obstruction between both treatment groups.

"Results of this sub-study demonstrate that intracoronary as compared to intravenous abciximab did not result in a difference in myocardial damage or reperfusion injury," said lead investigator Holger Thiele, MD. Dr. Thiele is Co-Director of the University of Leipzig - Heart Center in Germany.

"These findings confirm similarities in the combined endpoint of death, reinfarction and congestive heart failure found between the two methods in the AIDA STEMI trial," Dr. Thiele said.

Dr. Thiele will present the AIDA STEMI MRI sub-study on Thursday October 25 at 12:30 PM EST in the Main Arena (Hall D) at the Miami Beach Convention Center.

###

The trial was funded by Lilly Germany, the University of Leipzig - Heart Center and Clinical Trial Centre, and the Federal Ministry of Education and Research. Dr. Thiele reported research funding from Terumo, Lilly, Maquet Cardiovascular, and Teleflex Medical; consulting for Maquet Cardiovascular and Avidal; and speaker honoraria for Lilly, AstraZeneca, Daiichi Sankyo, Boehringer Ingelheim, Maquet Cardiovascular, and The Medicines Company.

About CRF

The Cardiovascular Research Foundation (CRF) is an independent, academically focused nonprofit organization dedicated to improving the survival and quality of life for people with cardiovascular disease through research and education. Since its inception in 1991, CRF has played a major role in realizing dramatic improvements in the lives of countless numbers of patients by establishing the safe use of new technologies and therapies in interventional cardiovascular medicine.

Transcatheter Cardiovascular Therapeutics (TCT) is the annual scientific symposium of the Cardiovascular Research Foundation. TCT gathers leading medical researchers and clinicians from around the world to present and discuss the latest developments in the field.

For more information, visit www.crf.org.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2012-10/crf-rot_3102512.php

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Copper rebounds from six-week low on China optimism

China's economy is slowly picking up from its weakest period of growth in three years, a survey of purchasing managers signaled, with new orders and output at their highest in months.

Analysts said the figures from the world's second largest economy had pushed three-month copper on the London Metal Exchange 0.9 percent higher to $7,903 per tonne by 0708 GMT.

The contract touched $7,807.75 the day before, its lowest level since September 7 and below key support at its 200-day exponential moving average.

"London copper is buoyed by today's PMI numbers, but Shanghai copper was mainly held back from further gains by a still-sluggish Chinese copper physical market," said Orient Futures analyst Andy Du.

The most active January copper contract on the Shanghai Futures Exchange edged up 0.4 percent to close at 57,500 yuan ($9,200) per tonne.

In a sign of weak downstream demand for Chinese copper, spot copper prices were trading at a discount of up to 200 yuan to the ShFE front month contract, a bigger spread than the previous session when that discount was only up to 100 yuan.

"Spot prices have been lower than front-month futures in China for some time now, a sign of weak downstream demand here and uncertainty over copper's outlook," said Du.

"For copper futures to stage a convincing rebound, we need to see Chinese consumption lifting."

For now, data suggests that the day's higher ShFE copper prices were largely due to short-covering as ShFE November copper's net daily open interest had fallen by 7,182 lots.

And despite signs pointing to China's economy stabilising, analysts warned the global economy was not out of the woods yet.

"Although there were some positive signals in the most recent data for China, the pace of growth has clearly slowed and uncertainties stemming from global demand and the fallout from previous policy tightening continue to cloud the outlook (for base metals)," National Australia Bank said in a client note.

Investors will be keeping an eye on the Fed's two-day meeting, which ends later in the session, although the U.S. central bank is likely to hold off from taking fresh steps, and will instead review the impact of the significant action it took last month.

Over the next few months, market players will also look out for new policies by Beijing that may affect metals demand, with a leadership change at the Communist Party Congress on November 8.

In industry news, China's copper imports jumped 6.93 percent on the year, largely due to the arrivals of term shipments booked last year rather than a spike in demand.

Base metals prices at 0708 GMT

Metal Last Change Pct Move YTD pct chg

LME Cu 7903.00 72.00 +0.92 3.99

SHFE CU FUT JAN3 57500 220 +0.38 3.36

LME Alum 1949.00 2.00 +0.10 -3.51

SHFE AL FUT JAN3 15420 30 +0.19 -2.65

HG COPPER DEC2 359.25 2.30 +0.64 4.55

LME Zinc 1866.00 19.00 +1.03 1.14

SHFE ZN FUT JAN3 14880 95 +0.64 0.57

LME Nickel 16375.00 20.00 +0.12 -12.48

LME Lead 2035.00 12.00 +0.59 0.00

SHFE PB FUT 15330 25 +0.16 0.26

LME Tin 20400.00 145.00 +0.72 6.25

LME/Shanghai arb 281

Shanghai and COMEX contracts show most active months

^ LME 3-m copper in yuan, including 17 pct VAT, minus SHFE third month

($1 = 6.2480 Chinese yuan)

(Reporting by Carrie Ho; Editing by Joseph Radford and Miral Fahmy)

?

Copyright 2012 Thomson Reuters. All rights reserved.

Source: http://www.ibtimes.com/copper-rebounds-six-week-low-china-optimism-852846

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Mortgage Loan Officer jobs surface ascent refinance and purchase ...

0 20px 10px Orange, CA (PRWEB) 23 October 2012

recent wave of mortgage officers are looking for steady work, is Anikim Credit Corp., by the suitable candidates lenders. The company has built relationships with bankers and financiers years, and says that it seems that markets turn on for some. The company representative said that there was a time, as a mortgage broker was on every corner, and there was a lot of loan officer job ? but it has slowly for many years. I am glad that the professional people who were in this business before to live again. Our phones are blanks with phone calls for a solid avenue loans location search picked up. With interest rates so low, and some prospective home buyers is at least 3 years from the foreclosure or short sale of the supermarket begin to see people buying houses again. The company sells to common Internet searches as a mortgage net branch and the Mortgage Loan Officer jobs and includinig many other terms that it is in the field, a major search engine.

Many people begin to mortgage banking business back you for a mortgage banker or a mortgage broker has the right to back-end search to get the job done. Anikimcreditcorp.com has spent years building the right relationships with their loan officers to fund loans. Representative of the company was quoted as loan programs basically all the same, the challenge has loan officers in order. A bank to finance the loans quickly Our company is proud to sell the loan originators to work with brokers Mortgage Bankers and FDIC banks. The advantages are that the mortgage loan officer can select what suits them best, based. On the type of structure they need to achieve their goals ?For more information about mortgage branch network opportunities and as always, a virtual loan officer, or VLO http://anikimcreditcorp.com visited the site

The company has seen a growth in the reverse mortgage division, especially in Southern California. Internet search terms such as a reverse mortgage San Diego and Los Angeles reverse mortgage have maintained stable over the past year. Advantage of loan officers in this market has grown, the company sources.

company, in particular, to the point where loan officers can fund loans quickly. And the company wants to growing markets (like California) in the last few months of 2012, then expand the number of countries in early 2013. According to the company, the company plans more than 1,000 new originators in 2013 to import, and do not see it that way. Anikim Credit Corp., the tools and techniques that are available today to help to realize their business. Use SEO to help businesses to promote the companys range of online marketing campaigns and the use of social media in real time to provide information about the mortgage loan officers and consumers. The company believes that by offering these Internet tools for mortgage loan officers can keep costs of marketing themselves as owners have an easier time rising costs. The company helps loan officers required by the institution all internet marketing tools to compete in today?s market.

us; Anikim Credit Corporation was to help to the mortgage crisis began, struggling loan officers and sales offices, mortgage banks, which were to be kept in a position in difficult times find. Since then, the company has built relationships with banks and brokers in the county and help the initiators failed in the right places in order to finance loans.

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ascent ? jobs ? Loan ? Mortgage ? Numbers ? Officer ? positive ? Purchase ? Refinance ? surface

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Source: http://www.stupeny.org/mortgage-loan-officer-jobs-surface-ascent-refinance-and-purchase-of-positive-numbers

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The Most Spectacular Mutation in Recent Human History

Globally, lactose intolerance is the norm; around two-thirds of humans cannot drink milk in adulthood

Photograph by Valentyn Volkov/iStockphoto/Thinkstock.

To repurpose a handy metaphor, let's call two of the first Homo sapiens Adam and Eve. By the time they welcomed their firstborn, that rascal Cain, into the world, 2 million centuries of evolution had established how his infancy would play out. For the first few years of his life, he would take his nourishment from Eve's breast. Once he reached about 4 or 5 years old, his body would begin to slow its production of lactase, the enzyme that allows mammals to digest the lactose in milk. Thereafter, nursing or drinking another animal's milk would have given the little hell-raiser stomach cramps and potentially life-threatening diarrhea; in the absence of lactase, lactose simply rots in the guts. With Cain weaned, Abel could claim more of his mother's attention and all of her milk. This kept a lid on sibling rivalry?though it didn't quell the animus between these particular sibs?while allowing women to bear more young. The pattern was the same for all mammals: At the end of infancy, we became lactose-intolerant for life.

Two hundred thousand years later, around 10,000 B.C., this began to change. A genetic mutation appeared, somewhere near modern-day Turkey, that jammed the lactase-production gene permanently in the ?on? position. The original mutant was probably a male who passed the gene on to his children. People carrying the mutation could drink milk their entire lives. Genomic analyses have shown that within a few thousand years, at a rate that evolutionary biologists had thought impossibly rapid, this mutation spread throughout Eurasia, to Great Britain, Scandinavia, the Mediterranean, India and all points in between, stopping only at the Himalayas. Independently, other mutations for lactose tolerance arose in Africa and the Middle East, though not in the Americas, Australia, or the Far East.

In an evolutionary eye-blink, 80 percent of Europeans became milk-drinkers; in some populations, the proportion is close to 100 percent. (Though globally, lactose intolerance is the norm; around two-thirds of humans cannot drink milk in adulthood.) The speed of this transformation is one of the weirder mysteries in the story of human evolution, more so because it's not clear why anybody needed the mutation to begin with. Through their cleverness, our lactose-intolerant forebears had already found a way to consume dairy without getting sick, irrespective of genetics.

Mark Thomas, an evolutionary geneticist at University College London, points out that in modern-day Turkey, where the mutation seems to have arisen, the warm climate causes fresh milk to rapidly change its composition. ?If you milk a cow in the morning,? he says, ?by lunchtime it's yogurt.?

Yogurt has plenty of benefits to confer, among them large testicles, swagger, and glossy fur?at least if you're a mouse?but most salient to our ancestors was that the fermentation process that transforms milk into yogurt consumes lactose, which is a sugar. This is why many lactose-intolerant people can eat yogurt without difficulty. As milk ascends what Thomas calls the ?fermentation ladder,? which begins with yogurt and culminates with virtually lactose-free hard cheeses, ever more lactose is fermented out. ?If you're at a party and someone says, 'Oh, I can't eat that?I'm lactose intolerant,' ? he says, ?you can tell them to shut up and eat the Parmigiano.?

Analysis of potsherds from Eurasia and parts of Africa have shown that humans were fermenting the lactose out of dairy for thousands of years before lactose tolerance was widespread. Here is the heart of the mystery: If we could consume dairy by simply letting it sit around for a few hours or days, it doesn't appear to make much sense for evolution to have propagated the lactose-tolerance mutation at all, much less as vigorously as it did. Culture had already found a way around our biology. Various ideas are being kicked around to explain why natural selection promoted milk-drinking, but evolutionary biologists are still puzzled.

?I've probably worked more on the evolution of lactose tolerance than anyone in the world,? says Thomas. ?I can give you a bunch of informed and sensible suggestions about why it's such an advantage, but we just don't know. It's a ridiculously high selection differential, just insane, for the last several thousand years.?

A ?high selection differential? is something of a Darwinian euphemism. It means that those who couldn't drink milk were apt to die before they could reproduce. At best they were having fewer, sicklier children. That kind of life-or-death selection differential seems necessary to explain the speed with which the mutation swept across Eurasia and spread even faster in Africa. The unfit must have been taking their lactose-intolerant genomes to the grave.

Milk, by itself, somehow saved lives. This is odd, because milk is just food, just one source of nutrients and calories among many others. It's not medicine. But there was a time in human history when our diet and environment conspired to create conditions that mimicked those of a disease epidemic. Milk, in such circumstances, may well have performed the function of a life-saving drug.

There are no written records from the period when humans invented agriculture, but if there were, they would tell a tale of woe. Agriculture, in Jared Diamond's phrase, was the ?worst mistake in human history.? The previous system of nourishment?hunting and gathering?had all but guaranteed a healthy diet, as it was defined by variety. But it made us a rootless species of nomads. Agriculture offered stability. It also transformed nature into a machine for cranking out human beings, though there was a cost. Once humans began to rely on the few crops that we knew how to grow reliably, our collective health collapsed. The remains of the first Neolithic farmers show clear signs of dramatic tooth decay, anemia, and low bone-density. Average height dropped by about 5 inches, while infant mortality rose. Diseases of deficiency like scurvy, rickets, beriberi, and pellagra were serious problems that would have been totally perplexing. We are still reeling from the change: Heart disease, diabetes, alcoholism, celiac disease, and perhaps even acne are direct results of the switch to agriculture.

Source: http://feeds.slate.com/click.phdo?i=d2b430203d107e3133f916a44c7130ae

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Coke Ad Forces Ordinary Folks Into A 007 Foot Chase - Business ...

Coca-Cola

Coke Zero's "Skyfall" video

The new Coke Zero "Skyfall" video is yet another textbook case of how to create a successful viral ad.

It's a simple idea, followed by an incredibly complicated execution: How do ordinary people react if they're suddenly forced into a James Bond-style foot chase through a crowded European railway station?

The spot was created by viral masters Duval Guillaume Modem, best-known for their Belgian TNT effort earlier this year, which featured unsuspecting villagers who find themselves in the middle of gunfights, runaway ambulances, and lingerie-wearing women on motorcycles.

Following a similar formula for Coke, Duval Guillaume Modem set up digital vending machines in an Antwerp train station to offer travelers free tickets to the launch of "Skyfall."

There's just one catch: the free tickets are on platform 6, and the punters are given only 70 seconds to get there.

As they race across the station, the befuddled commuters find themselves confronted with just the sort of nonsense that crops up in the movies ? two guys carrying a plate glass window at just the wrong moment, a fruit vendor spilling an avalanche of oranges, and so on.

It turns out that the guys who take up the challenge handle the assignment with a fair amount of grace:

Source: http://www.businessinsider.com/this-coke-ad-in-which-ordinary-folks-are-suddenly-forced-into-a-007-foot-chase-is-utterly-charming-2012-10

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Lebanese troops crackdown on militants after attack

This transcript is automatically generated

Think that's likely to come up tonight the rapidly deteriorating situation in Lebanon.

Troops in the capital Beirut launching a major crackdown after Friday's assassination of -- top intelligence official.

-- support violence in the streets of that city and beyond.

To -- Lebanese military officials chased away gunmen blaming the sectarian fighting for killing at least six people.

It follows Friday's huge bomb blast which killed a senior official -- been the critical of the Syrian regime's involvement in Lebanon.

We now have surveillance video which captured that -- and you can see people at the outdoor cafe.

When the powerful explosion sent shards of glass raining on the people's kids.

It also killed seven others and wounded dozens more some of them children who were just leaving school may have been -- for that.

-- on shares a border with Syria as I'm sure you know a nation that's been locked in a horrible city civil war for a year and a half or more.

Activist groups estimate more than 30000.

People have died in the last year and a half.

And now there are real concerns among foreign policy analysts that the violence -- just Billy across the border but it it could that it could ignite the conflict all across the region.

The Fox Report chief correspondent Jonathan shout and reported in that region often.

Including across Lebanon and specifically Beirut Jonathan authorities there are clearly trying to keep a lid on this.

Yeah I'm struggling might lead to do that -- we saw -- violent street protests.

Not just in Beirut today but in other cities as well including the northern city.

All of Tripoli the army then moved into this into the streets of Beirut and Tripoli.

And they did -- today get some measure of control but tensions remain at very high indeed amid suspicions.

The back -- bombing on Friday was carried out by Syrian agents with the sole purpose.

Silencing their critics in Lebanon listen.

There's a natural tendency for the Syrians to want to continue to exert control over that country it's and then of course you've got the players of Hezbollah Hamas.

All of those are in play in this particular case and did -- becomes it has since.

The -- proxy war that could take place if we're not careful.

And nobody wants that proxy wall hence the -- from US State Department officials today full all sides in Lebanon to exercise restraint.

Ted trying to achieve calm -- History tells us that may be difficult -- it's never been hard to stroke tensions in Lebanon.

It never has and you look at what the Arab Spring has turned out to be a -- across the region.

Much less about -- a much more a battle for control in so many of those countries between Shia.

And Sunni Muslims and take a look at the split in Lebanon.

27%.

-- 27%.

-- there is also a very large Christian population the majority of whom.

A maronite Christians in old -- seventeen.

Different religious -- recognized.

In Lebanon most of them have political wings the most powerful of those political wings is Hezbollah.

They stand to benefit the most from chaos in Lebanon they have calls strong allies not just a president a sad but also of the Ronnie and regime ship.

Jonathan thanks so much will have much more on tonight's debate live from South Florida.

Source: http://video.foxnews.com/v/1918330881001/lebanese-troops-crackdown-on-militants-after-attack/

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Business Negotiations: Cooperate to Claim Value

.

What happens in negotiations between two individuals who care little about each other?s outcomes?

Suppose an engineer and an industrial designer are arguing over the design of a car bumper. The designer only cares about whether the bumper matches the style of the vehicle; the engineer is concerned only about how the bumper connects to the front. After describing the trouble he?s having with the existing design, the engineer presents a solution that the designer deems ?ugly.? The designer threatens to involve her boss if the engineer doesn?t revert back to the prior design.

You?re the engineer ? what do you do?

First, balance your value-claiming strategies by working to create value. Ask the designer to explain where she thinks the new design went wrong, and identify possible solutions and low-priority issues on which you can offer tradeoffs. Second, remind her that there?s hope for a solution if you both let down your guard and work together. Third, listen openly to ?the designer?s proposals and try to build on them. Above all, ensure that your cooperative moves are reciprocated, or you?ll be vulnerable to exploitation.

Discover step-by-step techniques for avoiding common business negotiation pitfalls when you download a FREE copy of our Business Negotiation Skills: 5 Common Business Negotiation Mistakes special report from Harvard Law School.

Related Article: Accentuate the Positive

Would you like us to inform you when new Posts become available?

Source: http://www.pon.harvard.edu/daily/business-negotiations/business-negotiations-cooperate-to-claim-value/

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Obama, Romney Tied in Latest Poll (Voice Of America)

Share With Friends: | | Politics - Top Stories News, RSS and RSS Feed via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/257323625?client_source=feed&format=rss

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Private equity firm to buy Ancestry.com for $1.6B

Genealogy website Ancestry.com has agreed to be acquired by a group led by European private equity firm Permira Funds in a cash deal valued at about $1.6 billion.

The offered price of $32 per share is a nearly 10 percent premium over Friday's closing price of $29.18. Its shares jumped 8 percent, or $2.37, to $31.55 in premarket trading Monday.

Ancestry.com operates a website for researching family history and has more than 2 million paying subscribers. It says more than 10 billion records have been added to its site over the past 15 years.

The company said it has developed and acquired systems that digitize handwritten historical documents, and it works with government archives, historical societies and religious institutions around the world.

The company went public in 2009. Last year, it earned $62.9 million, or $1.29 per share, on nearly $400 million in revenue.

Ancestry.com said that the price represents a 41 percent premium over its closing price in early June before reports surfaced that the company had retained a financial adviser for a possible sale. Company shares have climbed from around $21 in early June and hit a 52-week high of $33.80 in early August before dropping back.

It said there will be no anticipated changes in its operating structure with the deal. The company will remain headquartered in Provo, Utah, and it will continue to focus on investing in content, technology and expanding product offerings in areas like DNA.

CEO Tim Sullivan and Chief Financial Officer Howard Hochhauser will keep a majority of their equity stakes, and Spectrum Equity will remain an investor. Spectrum owns a 30 percent stake in the company.

The company expects the deal to close early next year. It will announce third-quarter earnings on Wednesday.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2012-10-22-Ancestrycom-Acquisition/id-de3757799a6e43068bb1ee0a6e777b29

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Data Recovery Tips And Information - Find Somebody Who Can Help

I need Data Recovery assistance. This is something that many people utter on a daily basis. For one reason or the next, they have lost data on their computer and need to recover it as soon as possible. This happens to people using a home PC as well as those at work.

Although you may not realize it right now, just because you are having an issue with your computer does not mean that it has to last forever. It does not mean that your data is gone. You should realize that you may be able to recover the data as long as you take the right steps.

First things first, you should take note of what happened. This could be very useful if you hire a data recovery specialist in the near future. The more information you can provide the better.

Here are several other tips to keep in mind:
1. Don't do anything unless you know which steps you should be taking. One of the biggest mistakes you can make is attempt to recover the data on your own when you don't really know what you are doing. It is essential that you do as little as possible on your computer. Let a professional take the next steps. This way you know that things are being done the right way.
2. Shut down your computer. Many people neglect to do so because they want to continually attempt to find a repair. Chances are that you don't know what you are doing and you are just going to make things worse. Shut down your computer as you attempt to find somebody who can fix the problem. If you don't do this you are risking additional damage to your hard drive.
3. Contact a professional. There is no way of knowing if your data can be recovered until you contact somebody who has experience with this. As noted above, unless you know exactly what you are doing you should leave the job up to a professional.

Questions to Ask
Now that you know a little bit more about data recovery, you may have some questions on your mind. These questions should be directed towards somebody with knowledge and experience.

* What should I do next? This will ensure that you don't make any mistakes that could further jeopardize your system.
* How much will the data recovery process cost? This is going to be based on multiple factors, such as the cause, but it is a question that you need to ask nonetheless.
* What are the chances of success?

Nobody wants to think about the data recovery process. If you find yourself in this position it means that something has gone wrong with your PC. Fortunately, there is a solution if you can find a professional who can help.

Now that you know more about data recovery, including the tips and basic advice to follow, you may be able to get your PC back to normal in no time at all.

About the Author:
Aaron E. Earle is a world renowned data recovery expert. Learn more about data recovery tips, cost, and the process at the Data Recovery website.

Source: http://www.articlesnatch.com/Article/Data-Recovery-Tips-And-Information---Find-Somebody-Who-Can-Help/4224967

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Dogtober Fest, Black Cat Ball, Muttmixer and other pet events | Tails ...

Give your brain a workout at Dogtober Fest's trivia contest, flex some leg muscles at Woof Woof Walk and Dawg Dash or get gussied up in a costume for one of the other pet events happening this month.

Planning to add a pet to your home? See the adoption specials.

Got a pet event? Send information to tailsofseattle@seattletimes.com.

Dogtober Fest: 2-6 p.m. Oct. 20, Anchor Pub, 1001 Hewitt Ave., Everett. Test your beer and dog trivia knowledge at this event benefiting Scrub-a-Mutt and Everett's Animal Rescue Foundation (ARF). There will be a "whose dog?" photo contest, prizes and food. Must be 21 or over. Dogs welcome outside (weather pemitting).
http://www.everettarf.org/ and http://www.scrub-a-mutt.org/
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Woof Woof Walk: 9 a.m.-noon Oct. 20, Spanaway Park, 14905 Gus G. Bresemann Road S. (Military Road and Pacific Avenue), Spanaway. Walk, other activities and vendors at lakeside park. Registration is $20 for the first dog, $5 for second dog. T-shirts are $10. Food and blanket donations encouraged.
http://www.co.pierce.wa.us/pc/abtus/ourorg/parks/woofwalk.htm

Wildcard Weekend: 11 a.m.-5 p.m., Oct. 20, Central Washington Humane Society, 2405 W. Birchfield Road,Yakima. Microchip ID and vaccination clinic for pets. Adoption fees are reduced to $30 for dogs and $5 for cats all month.
http://www.yakimahumane.org/

Apple Day and Mutt Strut Dog Parade & Costume Contest: 11 a.m.-3 p.m. Oct. 20, Historic Bayview Corner, Whidbey Island. Event features food, fun and dogs in costume.
http://bayviewfarmandgarden.com/2012/09/28/its-time-once-again-for-apple-day-and-mutt-strut/
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Dawg Dash: 7:30 a.m. Oct. 21, University of Washington. Dog-friendly event with a 10K run and 5K run/walk. There also is a Husky Pups run for kids. This year's event is on the UW's upper campus. Check-in starts at 7:30 a.m. The 10K and 5K start at 9 a.m. For a complete schedule and parking details, see the website.
http://www.promotionevents.com/dawgdash/default.asp
???

The art work for the 15th annual Black Cat Ball poster and catalog was created by Aki Sogabe. This year's event is Oct. 27. Aki Sogabe / Courtesy of Purrfect Pals???

Black Cat Ball: Oct. 27, Meydenbauer Center, Bellevue. Halloween-themed gala includes a gourmet vegetarian sit-down dinner and auctions. The event benefits Purrfect Pals, a no-kill sanctuary that provides foster and hospice care for homeless cats. Tickets: $100.
http://www.purrfectpals.org/About/NewsAndEvents/CurrentEvents/BCB.asp

Howl-at-the-Moon Muttmixer: 6-8 p.m. Oct. 30, Woodmark Hotel, 1200 Carillon Point, Kirkland. Costume contest, treats for tricks and swag bags. RSVP to rsvp@citydogmagazine.com with the number of people and dogs planning to attend.
http://www.citydogmagazine.com/ and http://www.thewoodmark.com/

Fee Free Felines: Through Oct. 31. Regional Animal Services of King County, Pet Adoption Center 21615 64th Ave. S., Kent. The $55 adoption fee for cats six months and older is being waived this month. The cats are spayed/neutered, vaccinated, tested for feline leukemia and have microchip IDs. Adopted cats go home with a starter bag of food and a certificate for a free veterinary wellness exam, courtesy of the Seattle/King County Veterinary Medical Association.
http://www.kingcounty.gov/safety/regionalAnimalServices/News/2012/October/02NoFeeCatAdoptions.aspx

For more events, click here and scroll through the October list.

Source: http://seattletimes.com/html/tailsofseattle/2019478141_dogtober_fest_and_other_pet_events.html

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The Latest : Inglewood family of 6 shot, two killed, house set on fire ...

Google Maps

The red pin marks the block where a gunman has shot a family of six in Inglewood after setting their home on fire.

A father and his four-year-old son were killed and his wife and two other young children were wounded by a masked gunman who set fire to their home in?Inglewood.

[Update: 4:44 p.m.: "Our SWAT team is still working in the burnt building and we still have several units doing grid searches throughout about a 2 1/2 block radius around the site,?Lt. James Madia of the Inglewood Police Department said at a press conference. "We've put out a crime broadcast to agencies around the county. And we're starting to work with our partners at the federal level to get the word out so we can start expanding the size of the manhunt."]?

The shooting spree began around 4:30 a.m. this morning?at a residence on the 4900 block of W. 99th Street near the 405 freeway.

Five neighboring houses have been?evacuated as a SWAT team is using police dogs to search for the attacker, who may have lived in a rear house on the?property, Inglewood Police?Chief Mark Fronterotta told KABC.

"Right now we?re looking for a male black, 55, 5 foot 6, 160 pounds, wearing a dark ball cap and at the time of the shooting was wearing what people describe as a painter's mask,"?Lt. James Madia of the Inglewood Police Department told KPCC.

According to KTLA, officials say the home was set on fire prior to the gunfire. Firefighters were initially hampered from fighting the fire, which included the back guest house, because of the gunman who was believed to have been holed up in one of the structures.

Officials say a 6-year-old boy and a 7-year-old child are in critical but stable condition. Their mother was shot in the knee and the pelvis as she was trying to carry the youngest child out of the house.?The chief says the father was shielding two of his children when he was?shot.

Police have no?motive, but the gunman may have been a tenant who was recently evicted.

Meanwhile an 8-year-old child was also rushed to the hospital but doesn't seem to have any serious injuries.

Officials are asking neighbors stay inside their homes until the suspect is apprehended.

Source: http://www.scpr.org/blogs/news/2012/10/20/10619/inglewood-family-6-shot-two-killed-house-set-fire/

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Illinois congressman criticized over abortion remark

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Source: http://news.yahoo.com/illinois-congressman-criticized-over-abortion-remark-211211878.html

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What Was Life Like Before iPhones? [Humor]

Our children won't know what life was like before smartphones took over our every waking hour. But when you inevitably try to gather them around to tell them about all the time we spent not staring at screens? Well, as Doghouse Diaries points out, good luck with that: More »

Source: http://feeds.gawker.com/~r/gizmodo/full/~3/eDmRr_evg6M/what-was-life-like-before-iphones

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LG?s Rumored Nexus 4 Gets Caught On Film Again, Ahead Of Potential October 29 Unveiling

Considering the sheer volume of leaks and information floating around right now, it's becoming more and more clear that the so-called LG Nexus 4 is the real deal. In case you didn't already have enough to ponder though, the folks behind the infamous @evleaks Twitter account have gotten their hands on yet another photo of the unreleased device and a few new particulars about its size and weight.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/5YWyA1LOO5I/

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The 'Mortal Enemy' of Home Prices: Excess ... - Yahoo! Finance

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Housing data this week continue to point to a market recovery.

Housing starts surged to 4-year high last month the Commerce Department reported. New home construction increased 15% in September compared to August and building permits ? a number that reflects future building ? jumped 11.6% last month. Housing starts reached a seasonally adjusted annual rate of 872,000 units in September and single-family housing construction last month grew 11% to an annual rate of 603,000. New home building grew in three of four U.S. regions.

Forecasting firm IHS Global Insight called the housing starts number a "blowout." The National Association of Home Builders said its monthly builder sentiment survey was 41 in October, the highest level since June 2006. A reading below 50 represents negative sentiment about the market but the index has risen steadily over the past year.

Related: JP Morgan's Dimon Says Housing Has Turned the Corner: Is He Right?

Rising home prices and year-over-year increases in new and existing home sales have contributed to the turnaround in the housing market.

The latest positive numbers in the housing market have not persuaded economist Gary Shilling, a longtime housing bear, to change his downbeat forecasts. Shilling holds fast to his prediction that home prices will fall another 20% and dismisses talk that the market has bottomed. He cites the high number of shadow inventory in the market as support for his pessimistic housing thesis.

"Excess inventory is the mortal enemy of home prices," Shilling says in an interview with The Daily Ticker.

Related: More Good News on Housing But Hold the Champagne

Shadow inventory refers to the number of distressed homes that have not yet been listed by a realtor but are expected to hit the market soon; a number of the properties are in the process of foreclosure or are seriously delinquent or behind with loan payments.

Shilling contends that the uptick in housing data could very well be a head fake for the market. He says the "huge" overhang of excess inventory ? he pegs the number at 1.5 million ? will continue to hamper the recovery.

A new report by CoreLogic found that shadow inventory in July actually fell 10.2% from a year ago, the lowest point in three years. CoreLogic counted 2.3 million properties as shadow inventory in July, about a 6-month supply.

Related: Housing Recovery Stalled by Banks: Harvard Analyst

Shilling says he has also become concerned with the lack of new homebuyers entering the market. The rate for a 30-year fixed mortgage was 3.39% last week, near all-time record lows. He says speculators and investors are snapping up homes and hoping to flip them as a profit but new home owners "are the foundation of the market" he notes.

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Source: http://finance.yahoo.com/blogs/daily-ticker/mortal-enemy-home-prices-excess-housing-inventory-144251815.html

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Taylor Swift paints love "Red" in new album

LOS ANGELES (Reuters) - Country-pop star Taylor Swift has won over a legion of devoted fans in the past six years with her raw, honest lyrics of romance and heartbreak.

Now, at the grand age of 22, the five-time Grammy winner is says her new record "Red," to be released on Monday, "the most adventurous album I've ever made."

"'Red' is really kind of diary entries of the last two years of my life," Swift told Reuters in a telephone interview.

"There were beginnings and ends and there were ups and downs, and lessons that I learned and then had to learn all over again the exact same way ... the ups and downs of the whole experience of falling in love and being let down and letting go and starting over," she said.

"Red," Swift's follow-up to her 2010 best-seller "Speak Now," sees the singer-songwriter collaborate with the likes of British singer Ed Sheeran and pop music producer Max Martin.

The catchy pop-infused lead single "We Are Never Ever Getting Back Together" was an instant hit when it was released in September, becoming Billboard's most-downloaded first week digital single.

And like many of Swift's other songs, it had fans guessing over which of her many brief but high-profile romances she was referring to.

John Mayer? Joe Jonas? Taylor Lautner? Jake Gyllenhaal? Swift isn't telling.

"It helps me to know that 90 percent of what those little blog posts and articles say isn't true at all," said Swift, who is currently dating Conor Kennedy, 18, the son of Robert F. Kennedy Jr. "The one bit of privacy that I have is knowing that I know who inspired those songs and I don't tell anyone.

"For me, keeping my private life private and only sharing it with people through my music allows me to have that connection with my fans and not shut them out of anything. But it allows me to also have something that's just mine."

The singer has dealt with her fair share of critics expounding on everything from her music to her personal life. Although she used her Grammy-winning song "Mean" to send them a message, Swift claims she doesn't pay much attention to what people say.

"I don't really read anything so I don't know what's being said, which kind of allows me to make music from a pure place of just making the music that I love, Swift said. "People have been saying I was too pop since my first album so I'm used to that."

Along with music, Swift has become a branding powerhouse, with a line of lucrative sponsorship deals. She was named the highest-earning celebrity under 30 this year by Forbes magazine, which estimated her 2011 earnings to be $57 million.

Despite her superstar status, the singer is keen to keep herself grounded, crediting her friends for providing her with "some semblance of a normal life."

"I got to understanding how much I need my friends and how much I need to call them when I'm not around them ... because it turns out I am the kind of person that needs to run everything by my friends no matter what," Swift said with a laugh.

(Editing by Bill Trott)

Source: http://news.yahoo.com/taylor-swift-paints-love-red-album-003643091.html

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