Wednesday, February 27, 2013

Survey Anecdote Suggests We Have No Idea What?s Going On At Google+

googleplus-200-redBy Google's count, Google+ has over 500 million "upgraded" members and some 135 million people active "in just the stream." By researchers' best estimates, however, the answer is a bit more complicated.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/9EkEcL8o-fw/

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Crowdfunding expert Kendall Almerico explains ... - PR NewsChannel

(PR NewsChannel) / February 25, 2013 / TAMPA, Fla.?

ClickStartMeCrowdfunding expert Kendall Almerico, the CEO of ClickStartMe.com, recently released five simple rules entrepreneurs need to follow to start a new business using crowdfunding. Almerico says that using crowdfunding to start a business allows you to raise funds without giving away equity and creates a phenomenal marketing campaign for your new business if done correctly. Almerico notes that starting a business through crowdfunding is legal and discredits the common misconception that crowdfunding to start a business is prohibited by law.? ?Nothing could be further from the truth,? the crowdfunding guru notes. ?Crowdfunding a business start-up is completely legal in every state as long as you follow five simple rules.?

Misinformation about the legality of crowdfunding a start-up business generally comes from people in the financial industry who warn of advertising or selling stock or ownership in a business online without following SEC registration requirements, according to Almerico.?? ?This is red herring that banks, investment houses and venture capital firms want you to believe,? Almerico explains. ?Yes, the same banks, investment houses and venture capital firms who will not lend you any money to start or expand your business. They are scared to death of what crowdfunding will ultimately do to their business model.?

Here are Almerico?s five rules for new businesses to follow when they choose crowdfunding to start their business:

1.????? Do not give away equity or profit participation in your business when you crowdfund. Advertising to sell equity or profit participation could turn your crowdfunding project into a ?security? which can make your crowdfunding project run afoul of securities laws.? Instead, Almerico says, a crowdfunding project may give away ?rewards? in exchange for donations, but no equity in the business.? ?Besides,? Almerico points out, ?Why would you want to give away partial ownership in your business when you do not have to??? Almerico notes that with passage of the JOBS Act in 2012, selling equity through crowdfunding will become legal at some point, once the SEC creates rules in the coming months.

2.????? Do not treat crowdfunding donations as a loan to be repaid, with or without interest.? Loans and lending are heavily regulated industries in every state, and it could run afoul of a state lending law if you promise to repay a donation to your crowdfunding project.

3.????? Do not sell real estate. Like the lending industry, real estate is a very heavily regulated industry.? Selling, or offering to sell, a parcel of real estate can land you in trouble in some states. ?Land deals are best left to other funding vehicles,? Almerico says.

4.????? Do not sell or give away anything through crowdfunding that you would not be allowed to sell or give away in your state.? For example, if you want to give away bottles of wine as a reward in your business crowdfunding project, be sure you are legally allowed to sell or distribute wine in your state before you do so. ?And it goes without saying,? Almerico points out, ?that crowdfunding a business and giving away firearms, scheduled drugs, or anything illegal, would not be a smart idea.?

5.???????? If you have a question, ask a crowdfunding attorney.? Almerico knows this from his experience not only as a crowdfunding expert, but also as an attorney himself.? ?It never hurts to get legal advice if you are not sure,? Almerico says. ?But, be sure your business attorney has expertise in crowdfunding laws. Most business lawyers do not.?

Crowdfunding expert Kendall Almerico is the CEO of ClickStartMe.com, the upstart crowdfunding site that ?puts the fun in crowdfunding? and is a JOBS Act expert.? For more information or to schedule an interview with Kendall Almerico, e-mail media@clickstartme.com or call 813.410.4658.

MEDIA CONTACT
Tess Hottenroth
media@ClickStartMe.com???????????????????????????
(813) 410-4658

Direct link:??http://www.prnewschannel.com/2013/02/25/crowdfunding-expert-kendall-almerico-explains-how-to-start-business-using-crowdfunding/

SOURCE:??ClickStartMe.com

This press release is distributed by PR NewsChannel. Your News. Everywhere.

Source: http://www.prnewschannel.com/2013/02/25/crowdfunding-expert-kendall-almerico-explains-how-to-start-business-using-crowdfunding/

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Your health: perfect and intact?

A Christian Science perspective.

By Lyle Young / February 26, 2013

Your health is perfect and intact ? no matter how you may feel, look, or sound.

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Now, before you conclude that this is a preposterous statement, let me explain.

The conventional way of thinking is that life is material, that we develop over time, having our own thoughts and bodies ? and thus our own state of health ? all of which are governed by genes and by our life experience. According to this way of thinking, we live biologically and are governed by organic laws that dictate that illness is normal and self-evident reality. Logically then, at best we try to manipulate the body with surgery or drugs or with less invasive methods such as physiotherapy or change of diet.

But instead of considering that all that I?ve just described is reality, could it be that it?s actually a state of consciousness, a way of thinking that we may have unwittingly adopted but that we can consciously change?

The founder of the Monitor, Mary Baker Eddy, contributed not only to journalism but also to health and health care. Sick for years, she teetered between living and dying. But in the Bible, her solace, she saw that the healings of Jesus were not miraculous but a natural expression of his understanding of the true nature of health. In the 1860s, when she was in her late 40s, she came to understand her way out of the health theories prevalent at that time. This restored her health, allowing her to serve society vigorously for another four decades. She began to teach this understanding, both in person and through her books. (Her main work, ?Science and Health with Key to the Scriptures,? was first published in 1875.) Soon, many of her students were practicing this method of healing, and teaching others, too. Her method of healing is not faith healing as it?s popularly known. Rather, it?s based on deep spiritual insights about the nature of identity, insights that Mrs. Eddy found in the Old and New Testaments of the Bible.

Eddy, a keen observer of human thinking, identified the kinds of thoughts that lead to illness. She saw that sickness is an unnatural, unconscious deviation from the perfection of God and of each one of us as His image and likeness. She came upon a place in thought at which individuals adopt a concept of themselves that leads either to discord and sickness or to holiness and health. She discovered that everyone can become aware of their thoughts and respond obediently to thoughts from God, those thoughts being spiritual, pure, and healthy. For her, mental self-awareness is key ? just as knowing how you?re spending money is essential to sound personal finance.

Most especially, Eddy discovered in the Bible that there?s a reliable source for healthy thoughts ? God, the one divine Mind ? that knows each of us, God?s children, as spiritual, perfect, free, and well. This fundamental truth, though not visible physically, gives each of us a strong platform from which to claim and even demonstrate that we are healthy.

Try this: Instead of assuming that you?re largely a set of body parts that can become ill, feel your oneness with this purely good, infinite Mind as its spiritual reflection. Start from the standpoint that your health is intact because goodness and wellness are inherent in this one infinite God that you reflect. This way of thinking has made a vast difference in my life, giving me both a more moral approach to living and better health. It can do the same for you.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/2inm-XDvkws/Your-health-perfect-and-intact

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Linking insulin to learning: Insulin-like molecules play critical role in learning and memory

Feb. 26, 2013 ? Though it's most often associated with disorders like diabetes, Harvard researchers have shown how the signaling pathway of insulin and insulin-like peptides plays another critical role in the body -- helping to regulate learning and memory.

In addition to showing that the insulin-like peptides play a critical role in regulating the activity of neurons involved in learning and memory, a team of researchers led by Yun Zhang, Associate Professor of Organismic and Evolutionary Biology, show that the interaction between the molecules can fine-tune how, or even if, learning takes place. Their work is described in a February 6 paper in Neuron.

"People think of insulin and diabetes, but many metabolic syndromes are associated with some types of cognitive defects and behavioral disorders, like depression or dementia," Zhang said. "That suggests that insulin and insulin-like peptides may play an important role in neural function, but it's been very difficult to nail down the underlying mechanism, because these peptides do not have to function through synapses that connect different neurons in the brain"

To get at that mechanism, Zhang and colleagues turned to an organism whose genome and nervous system are well described and highly accessible by genetics -- C. elegans.

Using genetic tools, researchers altered the small, transparent worms by removing their ability to create individual insulin-like compounds. These new "mutant" worms were then tested to see whether they would learn to avoid eating a particular type of bacteria that is known to infect the worms. Tests showed that while some worms did learn to steer clear of the bacteria, others didn't -- suggesting that removing a specific insulin-like compound halted the worms' ability to learn.

Researchers were surprised to find, however, that it wasn't just removing the molecules that could make the animals lose the ability to learn -- some peptide was found to inhibit learning.

"We hadn't predicted that we would find both positive and negative regulators from these peptides," Zhang said. "Why does the animal need this bidirectional regulation of learning? One possibility is that learning depends on context. There are certain things you want to learn -- for example, the worms in these experiments wanted to learn that they shouldn't eat this type of infectious bacteria. That's a positive regulation of the learning. But if they needed to eat, even if it is a bad food, to survive, they would need a way to suppress this type of learning."

Even more surprising for Zhang and her colleagues was evidence that the various insulin-like molecules could regulate each other.

"Many animals, including the humans, have multiple insulin-like molecules and it appears that these molecules can act like a network," she said. "Each of them may play a slightly different role in the nervous system, and they function together to coordinate the signaling related to learning and memory. By changing the way the molecules interact, the brain can fine tune learning in a host of different ways."

Going forward, Zhang said she hopes to characterize more of the insulin-like peptides as a way of better understanding how the various molecules interact, and how they act on the neural circuits for learning and memory.

Understanding how such pathways work could one day help in the development of treatment for a host of cognitive disorders, including dementia.

"The signaling pathways for insulin and insulin-like peptides are highly conserved in mammals, including the humans," Zhang said. "There is even some preliminary evidence that insulin treatment, in some cases, can improve cognitive function. That's one reason we believe that if we understand this mechanism, it will help us better understand how insulin pathways are working in the human brain."

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Story Source:

The above story is reprinted from materials provided by Harvard University.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Zhunan Chen, Michael Hendricks, Astrid Cornils, Wolfgang Maier, Joy Alcedo, Yun Zhang. Two Insulin-like Peptides Antagonistically Regulate Aversive Olfactory Learning in C.?elegans. Neuron, 2013; 77 (3): 572 DOI: 10.1016/j.neuron.2012.11.025

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/HFukdteMQE0/130226162837.htm

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Tuesday, December 11, 2012

Dumbest People Of 2012?

Dumb As A Blog:

Dumb people come and go every year, and 2012 was no different.

The past 12 months saw some epic stupidity, and not just from famous generals who had affairs with their biographers, men still dating the women who bit off their testicles, or the CEO who oversaw the death of the Twinkie.

The folks at Dumb As A Blog were smart enough to find those people and 17 more.

Read the whole story at Dumb As A Blog

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Source: http://www.huffingtonpost.com/2012/12/10/dumbest-people-of-2012_n_2273479.html

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Today's Woman Review & Giveaway Blog ? KInderglo nightlights

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There are monsters in the closet,? and a boogeyman hiding under the bed. ?Many children have a fear of the dark, but there are some things we can do to help kids overcome that fear. Make your child feel comfortable. Show them that there?s nothing in the closet, under the bed? and it is their teddy bear in the corner. Positively assure? them that no harm will come to them and that you are close by.? Provide support for your child by placing a nightlight in their room.? Nightlights can be an effective way to help children feel more secure at night. For parents, it can be the only way to ensure that? you get a full night?s sleep.

There are many different kinds of night lights on the market. Our personal favorite happens to be KinderGlo nightlights.? Shaped? like characters these rechargeable nightlights are made of a non-toxic plastic that won?t ever get hot to the touch, meaning your child can carry? them with them to the bathroom or cuddle with them in bed.

Pressing the light button on the bottom of the KinderGlo nightlight figure will turn on the nightlight and select continually changing colors or a constant single color of blue, red or green. The night light automatically dim and shuts off after 30 minutes in all color settings,? or parents can press and hold the button for three seconds to keep the KinderGlo on all night.

We were sent Hootie to review. Hooties is about 5 inches tall and has all the same features common as the KinderGlo Night Lights.? Currently, there are 8 different adorable characters to choose from and? they are available for only $24.95 at the Kinderglo Store and Amazon.

Sleep? is particularly important for children, as it directly impacts mental and physical development. A Kinderglo makes sleep time easier and would make a great gift for any child who is afraid of the dark.

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I received the KinderGlo Quarter Moon LED Night Light from Blue Moon Lites, Inc. in order to write my review. No other compensation was received.


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? Kinderglo Night Light Review and Giveaway
? 2012 Christmas Gift Guide

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Source: http://www.todays-woman.net/blog/2012/baby-product-reviews/kinderglo-2/

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McAfee wants to return to US, 'normal life'

In this photo released by Guatemala's Human Rights Ombudsman's office, software company founder John McAfee is photographed in an immigration detention center in Guatemala City, Thursday, Dec. 6, 2012. The anti-virus guru was arrested at a hotel in an upscale neighborhood with the help of Interpol agents, hours after he said he would seek asylum in the Central American country. Guatemalan authorities were awaiting orders from their Foreign Ministry about whether to send him back to Belize, where he is a person of interest in the killing of a fellow expatriate American. (AP Photo/Guatemala's Human Rights Ombudsman's office)

In this photo released by Guatemala's Human Rights Ombudsman's office, software company founder John McAfee is photographed in an immigration detention center in Guatemala City, Thursday, Dec. 6, 2012. The anti-virus guru was arrested at a hotel in an upscale neighborhood with the help of Interpol agents, hours after he said he would seek asylum in the Central American country. Guatemalan authorities were awaiting orders from their Foreign Ministry about whether to send him back to Belize, where he is a person of interest in the killing of a fellow expatriate American. (AP Photo/Guatemala's Human Rights Ombudsman's office)

(AP) ? Software company founder John McAfee says he wants to return to the United States and "settle down to whatever normal life" he can.

McAfee says "I simply would like to live comfortably day by day, fish, swim, enjoy my declining years."

The off-beat McAfee answered what he claimed were reporters' questions during a live-stream Internet broadcast from the Guatemalan detention center where he is fighting a government order he be returned to Belize.

Police in neighboring Belize want to question McAfee in the fatal shooting of a U.S. expatriate who lived near his home on a Belizean island. McAfee has denied involvement in the killing.

McAfee said Sunday he blacked out and hit his head earlier in the week after not eating and smoking "almost non-stop."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2012-12-09-Guatemala-McAfee/id-2c0455e2a8264cfe8784101766641171

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